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不同免疫途径对蛋用鸡分泌型免疫球蛋白A细胞分布的影响
引用本文:杨倩,黄国庆,毛卫华,王红丽.不同免疫途径对蛋用鸡分泌型免疫球蛋白A细胞分布的影响[J].中国兽医科学,1998(11).
作者姓名:杨倩  黄国庆  毛卫华  王红丽
作者单位:南京农业大学动物医学院
摘    要:用鸡新城疫弱毒疫苗通过饮水、滴鼻和肌肉注射免疫蛋用鸡,以葡萄球菌A蛋白辣根过氧化酶和兔抗鸡分泌型免疫球蛋白A(SIgA)间接组织化学染色,显示消化道相关淋巴组织(GALT)和呼吸道相关淋巴组织(RALT)中SIgA细胞的生成及分布。结果表明,滴鼻和饮水免疫组蛋用鸡GALT和RALT中产生SIgA细胞较早且多,并于首免后28d达最高峰,一直持续到首免后56d。肌肉注射组蛋用鸡SIgA细胞在各相应部位数量较少,且持续时间较短。

关 键 词:免疫途径  蛋用鸡  呼吸道相关淋巴组织  消化道相关淋巴组织  分泌型免疫球蛋白A

Effect of Immune Ways on the Distribution of Immunoglobulin A secreting cells in layers
Yang Qian,Huang Guoqing,Mao Weihua,Wang Hongli.Effect of Immune Ways on the Distribution of Immunoglobulin A secreting cells in layers[J].Veterinary Science in China,1998(11).
Authors:Yang Qian  Huang Guoqing  Mao Weihua  Wang Hongli
Abstract:Layers were immunized with newcastle disease attenuated vaccine by oral, nasal and muscle inoculation to observe the immunoglobulin A secreting cells (SIgA) in gut associated lymphoid tissue (GALT) and respiratory tract associated lymphoid tissue (RALT), by means of staphyloccocus protein A horseradish peroxidase and rabbit anti chicken immunoglobulin A secreting (SIgA) cells indirect histochemical staining method. The results showed that the SIgA cells yielded more and earlier in oral and nasal immune treatment than in muscle inoculation and reached the peak value on the 28th day after the first vaccination which lasted 28 days.
Keywords:immune ways  layers  gut  associated lymphoid tissue  respiratory tract  associated lymphoid tissue  immunoglobulin A  secreting cells
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