| 特异性IgY抗仔猪断奶腹泻机理的研究概况 |
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| 引用本文： | 由昭红,姜中其. 特异性IgY抗仔猪断奶腹泻机理的研究概况[J]. 中国兽医科学, 2005, 35(10): 832-836 |
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| 作者姓名： | 由昭红 姜中其 |
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| 作者单位： | 浙江大学,动物科学学院,浙江,杭州,310029 |
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| 基金项目： | 浙江省科技厅资助项目(2003C32002)，浙江省教育厅资助项目(20000240) |
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| 摘 要： | 针对仔猪断奶腹泻(Post-weaningEscherichia colidiarrhea,PWECD)这一仔猪断奶后的常见病和多发病的病原特异性,阐述了利用K88和F18等特异性菌毛作为抗原免疫产蛋母鸡制备的抗PWECD特异性卵黄抗体对大肠埃希氏菌引起的断奶仔猪腹泻的作用机理。认为,特异性IgY用于防治PWECD,具有安全、高效、成本低、产率高、稳定性好,无药物残留,不会产生耐药性,符合现代动物管理理念等诸多优点,是一种能有效防治PWECD的绿色生物制剂,应用前景广阔。
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| 关 键 词： | 卵黄抗体 仔猪断奶腹泻 产肠毒素型大肠埃希氏菌 菌毛 |
| 文章编号： | 1000-6419(2005)10-0832-05 |
| 修稿时间： | 2005-07-20 |
Situation of study on specific IgY against post-weaning Escherichia coli diarrhea in piglets |
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| YOU Zhao-hong,JIANG Zhong-qi. Situation of study on specific IgY against post-weaning Escherichia coli diarrhea in piglets[J]. Chinese Veterinary Science, 2005, 35(10): 832-836 |
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| Authors: | YOU Zhao-hong JIANG Zhong-qi |
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| Abstract: | The specific chicken-egg-yolk antibody(IgY) which was developed from laying hens immuned with K88 and F18 fimbriae,and the mechanism of the antibody against post-weaing Escherichia coli diarrhea(PWECD) were expounded in the light of specificity of the causal agent leading to PWECD with a high rate of incidence.With being characterized by safety,high efficiency,low production cost,high yield,good stability,free antibiotic residues and no induction of antibiotic resistance,IgY was considered as a kind of green bio-preparation and would be applied widely in the future. |
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| Keywords: | egg-yolk antibody post-weaning diarrhea in piglet enterotoxigenic Escherichia coli (fimbriae) |
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