| 损伤皮肤中白三烯B_4含量测定与损伤时间推断 |
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| 引用本文： | 孙洪涛,祝家镇. 损伤皮肤中白三烯B_4含量测定与损伤时间推断[J]. 中国法医学杂志, 1992, 0(1) |
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| 作者姓名： | 孙洪涛 祝家镇 |
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| 作者单位： | 中山医科大学法医病理学教研室，中山医科大学法医病理学教研室 广州 510089，广州 510089 |
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| 摘 要： | 本文作者利用高压液相色谱,快速检测大鼠皮肤切创创缘组织中白三烯B_4含量。结果发现,生前各损伤时间组创缘中白三烯B_4含量明显升高,且在1小时内与损伤时间有一定线性关系;死后损伤标本未见白三烯B_4含量升高。由此表明白三烯B_4含量测定,对推断生前1小时内的损伤时间有重要价值。高压液相色谱能快速、准确地检测损伤组织中的白三烯B_4。
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| 关 键 词： | 白三烯B_4(LTB_4) 皮肤切创 高压液相色谱(HPLC) |
THE DETERMINATION OF THE CONTENT OF LTB_4 IN SKIN INCISIONS |
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| Sun Hongtao Zhu Jia zhen. THE DETERMINATION OF THE CONTENT OF LTB_4 IN SKIN INCISIONS[J]. Chinese Journal of Forensic Medicine, 1992, 0(1) |
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| Authors: | Sun Hongtao Zhu Jia zhen |
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| Affiliation: | Sun Hongtao Zhu Jia zhen Department of Forensic pathology,Sun yat-Sen University of Medical Sciences,Guangzhou 510089 |
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| Abstract: | The Content of LT B_4 in the edge of 36 SD rats were determined by HPLC. It was found that the content of LTB_4 in the anternortem wounds is markedly increased, and has certain linear relationship with time of injury within one hour. No increasing of LTB_4 could be found in the postmortem wounds. It indicates that it is very valuable to estimate time of injury by determining LT B_4 content in wound edge, The content of LTB_4 in wound edge can be determined rapidly and accurately with HPLC. |
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| Keywords: | Leukotriene B_4(LTB_4) Skin cutting wound High performance liquid chromatographic (HPLC) |
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