| 岫岩满族9个STR基因座遗传多态性 |
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| 引用本文： | 袁丽,鲁涤,石美森,杨雪. 岫岩满族9个STR基因座遗传多态性[J]. 法律与医学杂志, 2011, 0(5) |
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| 作者姓名： | 袁丽 鲁涤 石美森 杨雪 |
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| 作者单位： | 司法部司法鉴定科学技术研究所上海市法医学重点实验室;证据科学教育部重点实验室(中国政法大学); |
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| 基金项目： | 上海市法医学重点实验室开放课题(课题号KF1003) |
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| 摘 要： | 目的用复合荧光扩增体系调查辽宁鞍山岫岩满族无关个体D6S1043、D7S3048、D9S925、D11S2368、D14S608、D15S659、D17S1290、D20S470和GATA198B05等9个STR基因座的遗传多态性。方法用本实验室构建的9个常染色体STR基因座荧光复合扩增体系,对辽宁鞍山岫岩满族252个无关个体的DNA进行PCR扩增,3130型基因分析仪电泳检测扩增产物及等位基因分型标准物,GeneMapper誖3.2分析软件中导入本体系Panel和Bin,对电泳结果进行分析,按照重复序列重复次数命名等位基因,使用Power-StatsV12和GENEPOP软件进行统计学分析。结果 9个STR基因座在辽宁鞍山岫岩满族基因型频率分布均符合Hardy-Weinberg平衡(P﹥0.05),多态性信息含量在0.750～0.860之间,杂合度在0.794～0.881之间,个体识别力在0.918～0.968之间,非父排除概率在0.587～0.757之间,累积非父排除率为0.999 96,累积个体识别能力为0.999 999 999 999 1。结论这9个非CODIS系统STR基因座在鞍山岫岩满族群体中等...
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| 关 键 词： | 法医生物学 短串联重复序列 遗传多态性 岫岩满族 |
Genetic Polymorphism of 9 CODIS Short Tandem Repeat Loci in Xiuyan Manchu Population |
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| Yuan Li,Lu Di,Shi Meisen,et al.. Genetic Polymorphism of 9 CODIS Short Tandem Repeat Loci in Xiuyan Manchu Population[J]. The Journal of Law & Medicine, 2011, 0(5) |
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| Authors: | Yuan Li Lu Di Shi Meisen et al. |
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| Affiliation: | Yuan Li,Lu Di,Shi Meisen,et al.Shanghai Key Lab of Forensic Medicine,Shanghai 200063 |
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| Abstract: | Objective To investigate the genetic polymorphisms of 10 short tandem repeats loci(D6S1043,D7S3048,D9S925,D11S2368,D14S608,D15S659,D17S1290,D20S470 and GATA198B05) in Liaoning Anshan Xiuyan Man population.Methods We used a multiplex system developed by ourselves to amplify 252 Xiuyan Man population unrelated individual's DNA.The amplified fragments were separated by electrophoresis in 3130 Genetic Analyzer.We used GeneMapper R3.2 software to analyze these results.Results The distributions of genotype for 9 ... |
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| Keywords: | Forensic biology Short tandem repeats Genetic polymorphism Xiuyan Manchu Population |
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