Identification of two cannabimimetic compounds WIN48098 and AM679 in illegal products |
| |
| Authors: | Adolfo Gregori Fabio Damiano Maurizio Bonavia Valentina Mileo Francesco Varani Maria Monfreda |
| |
| Institution: | 1. Carabinieri, Department of Scientific Investigation, via Parco Ducale 3, 43126 Parma, Italy;2. University of Modena e Reggio Emilia, Department of Chemistry, via Campi 183, 41100 Modena, Italy;3. Chiesi Farmaceutici S.p.A, Preclinical R&D, Analytics and Early Formulations Department, Via Palermo 26/A, 43122 Parma, Italy;4. Italian Customs Agency, Central Directorate for Product Analysis and Chemical Laboratories, via Mario Carucci 71, 00143 Rome, Italy |
| |
| Abstract: | Two synthetic cannabinoids have been identified, during a survey, as new adulterants; they might have been intended to be used as ingredients for smart drugs. The characterization of these compounds has been made by gas chromatography–mass spectrometry (GC–MS), Orbitrap high resolution mass spectrometry (HRMS) and nuclear magnetic resonance (NMR), leading to the identification of WIN48098, a compound disclosed as a new adulterant in herbal and powder products, and AM679, identified in Italy for the first time.Taking into account the high number of synthetic cannabinoids seized during the last year in Italy, how quickly they appear on the illegal market and the rapidity required for analytical results, a method was developed for the simultaneous quantitation of several synthetic cannabinoids, using gas chromatography–flame ionization detection (GC–FID). |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
