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Genetic polymorphism of desialyzed alpha 2 HS-glycoprotein by ultrathin isoelectric focusing
Authors:I M Sebetan  M M Heshmat
Affiliation:Department of Forensic Medicine, Tohoku University School of Medicine, Sendai, Japan.
Abstract:The genetically determined polymorphism of alpha 2 HS-glycoprotein was analyzed by immunoblotting ultrathin-layer polyacrylamide gel isoelectric focusing in the pH range 4-6.5 and neuraminidase pretreated sera. In a Libyan population sample from Tripoli (n = 110) three common phenotypes, alpha 2 HSG 1-1, 2-1, and 2-2, were observed. The allele frequencies were alpha 2 HSG1 = 0.8364 and alpha 2 HSG2 = 0.1636. The theoretical exclusion rate in cases of disputed paternity is 11.8%.
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