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| 大鼠死后肝脏磷酸果糖激酶-2含量的变化 | |
| 作者姓名： | Jin J Li B Jiao BG Fu J Huang H Song Y Peng QY Liao ZG |
| 作者单位： | 1. 四川大学华西基础医学与法医学院,四川,成都,610041 2. 四川华大司法鉴定所,四川,成都,610041 3. 电子科技大学医院,四川,成都,610054 4. 四川大学华西公共卫生学院,四川,成都,610041 |
| 摘 要： | 目的 分析不同死亡时间和死亡原因大鼠肝脏组织内磷酸果糖激酶-2(PFK-2)含量的变化.方法 大鼠105只随机分为三组,以不同方式(失血、窒息、断颈)处死.分别于死后0、1、2、4、8、12和24h取大鼠肝脏组织,免疫组化和图像分析技术测定大鼠PFK-2变化.结果 三组不同死亡原因大鼠肝脏组织内PFK-2的含量随死亡时间延长呈规律性减弱趋势.结论 大鼠肝脏组织内PFK-2的变化可以反映死亡时间的变化趋势. |
| 关 键 词： | 死亡时间 磷酸果糖激酶-2 含量 肝组织 |
| 文章编号： | 1004-5619(2007)02-0084-03 |
| 修稿时间： | 2006年10月18 |
Postmortem changes of liver phosphofructokinase-2 level in rats following different causes of death |
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| Jin J,Li B,Jiao BG,Fu J,Huang H,Song Y,Peng QY,Liao ZG.Postmortem changes of liver phosphofructokinase-2 level in rats following different causes of death[J].Journal of Forensic Medicine,2007,23(2):84-85,89,F0002. | |
| Authors: | Jin Ju Li Bin Jiao Bai-Guang Fu Jia Huang Hong Song Yu Peng Qi-Yi Liao Zhi-Gang |
| Institution: | West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China. |
| Abstract: | Objective To study the changes of liver phosphofructokinase-2(PFK-2) level at different postmortem intervals as well as due to different causes of death.Methods One hundred and five rats were randomly divided into 3 groups and the rats were sacrificed by either bleeding,suffocating,and neck breaking,respectively.The content of liver PFK-2 at 0,1,2,4,8,12 and 24 hours following death were studied using immunohistochemishtry and image analysis.Results PFK-2 content of the rat's liver in all 3 groups showed a linear decrease at different postmortem intervals with no significant statistical differences found between the different groups.Conclusion PFK-2 level in rat liver appears to decrease linearly in correlation with prolonged PMI. |
| Keywords: | postmortem interval phosphofructokinase-2(PFK-2) content liver tissue |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |