Blood versus bone marrow pentobarbital concentrations |
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Authors: | C L Winek A G Costantino W W Wahba W D Collom |
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Affiliation: | Allegheny County, Department of Laboratories and Duquesne University, 542 Fourth Avenue, Pittsburgh, PA 15219 U.S.A. |
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Abstract: | Postmortem pentobarbital levels in rabbit heart blood and bone marrow were determined and compared. The average ratio of femur marrow/blood pentobarbital concentrations in 24 rabbits was 1.06 +/- 0.05. The average percent difference between actual plasma pentobarbital concentrations and calculated plasma pentobarbital concentrations was 5.82 +/- 1.96. Concentrations were determined by gas chromatography of extracted, derivatized pentobarbital. |
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Keywords: | Pentobarbital Bone marrow Gas liquid chromatography Flame ionization detector Marrow/plasma ratio |
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