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Blood versus bone marrow pentobarbital concentrations
Authors:C L Winek  A G Costantino  W W Wahba  W D Collom
Affiliation:Allegheny County, Department of Laboratories and Duquesne University, 542 Fourth Avenue, Pittsburgh, PA 15219 U.S.A.
Abstract:Postmortem pentobarbital levels in rabbit heart blood and bone marrow were determined and compared. The average ratio of femur marrow/blood pentobarbital concentrations in 24 rabbits was 1.06 +/- 0.05. The average percent difference between actual plasma pentobarbital concentrations and calculated plasma pentobarbital concentrations was 5.82 +/- 1.96. Concentrations were determined by gas chromatography of extracted, derivatized pentobarbital.
Keywords:Pentobarbital  Bone marrow  Gas liquid chromatography  Flame ionization detector  Marrow/plasma ratio
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