Genetic characterization of a population from Cauca Department with 15 STRs markers |
| |
| Affiliation: | 1. GENES Ltda, Medellín, Colombia;2. Instituto de Biología, Universidad de Antioquia, Medellín, Colombia;3. Universidad de Pamplona, Colombia;4. Universidad Pontificia Bolivariana, Medellín, Colombia;1. Armed Forces DNA Identification Laboratory, Armed Forces Medical Examiner System, United States;2. American Registry of Pathology, United States;3. Flinders University, Australia;4. National Institute of Standards and Technology, United States;1. IdentiGEN – Genetic Identification Laboratory and Research Group of Genetic Identification, School of Natural and Exact Sciences (FCEN), University of Antioquia, Medellin, Colombia;2. Institute of Forensic Sciences, Genomic Medicine Group, University of Santiago de Compostela, Galicia, Spain;3. Technological University of Pereira, Colombia;4. IPATIMUP, Institute of Molecular Pathology and Immunology of the University of Porto, Portugal;5. DNA Diagnostic Laboratory (LDD), State University of Rio de Janeiro (UERJ), Rio de Janeiro – RJ, Brazil;1. Laboratorio de Genética Molecular de Cruz Vital – Cruz Roja Ecuatoriana Quito, Ecuador;2. Laboratorio GENES Ltda, Medellin, Colombia;1. Physical Anthropology Lab, School of Medicine, Granada University [Universidad de Granada], Avenida de Madrid 11, 18012, Granada, Spain;2. GIEBSCUERPO Research Group, Human and Social Sciences Department, Antioquia University [Universidad de Antioquia], Calle 67 No. 53—108 Bloque 9, Medellin, Colombia;3. Radiology Unit, San Vicente de Paul University Hospital [Hospital Universitario San Vicente de Paúl], Calle 64 N°5D—154, Medellin, Colombia |
| |
| Abstract: | This study established allele frequencies and some parameters of forensic interest with 15 autosomal STRs markers in a sample of 172 unrelated individuals from the Department of Cauca – Colombia using the PowerPlex® 16 BIO System (Promega CO) and Qiagen Multiplex PCR (Qiagen) kits. All markers analyzed showed more than 61% of heterozygosity. Penta E and Penta D were the only systems that are not in Hardy Weinberg equilibrium (p < 0.0033) after Bonferroni correction. The probabilities of paternity (W), the power of exclusion (PE) and of discrimination (PD) accumulated for all loci analyzed were 0.9999, 0.9999 and >0.9999, respectively. The parameters of forensic interest have values suitable for routine use in forensic genetics. |
| |
| Keywords: | AND STR Cauca Department Genes Ltda Colombia Paternity test |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
