| 4个STR基因座在广东汉族人群的单倍型分布 |
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| 引用本文： | 吕德坚,刘秋玲,李建金,伍新尧. 4个STR基因座在广东汉族人群的单倍型分布[J]. 中国法医学杂志, 2000, 15(Z1): 25-27 |
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| 作者姓名： | 吕德坚 刘秋玲 李建金 伍新尧 |
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| 作者单位： | 中山医科大学法医学系,广州,510089 |
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| 基金项目： | 本课题系中山医科大学211项目资助 |
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| 摘 要： | 调查DYS19、DYS390和DYS389Ⅰ/Ⅱ基因座在广东汉族群体的单倍型分布。PCR扩增后,用不连续PAGE电泳系统分型。在130名无关男性个体中,共检出81种不同的单倍型,其中52种只出现过1次。4个基因座单倍型的遗传多样性、个体识别率和非父排除率分别为0.9989,0.9824,0.9824,结果表明,4个STR基因座的单倍型检测在法医学个体识别和亲权鉴定方面有较高的应用价值。
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| 关 键 词： | Y染色体 单倍型 短串联重复序列(STR) 广东汉族人群 |
| 修稿时间： | 1999-11-01 |
Distribution of four STR loci's haplotypes in Guangdong Han Population |
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| /LU Dejian,LIU Qiuling,LI Jianjin,et al.. Distribution of four STR loci's haplotypes in Guangdong Han Population[J]. Chinese Journal of Forensic Medicine, 2000, 15(Z1): 25-27 |
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| Authors: | /LU Dejian LIU Qiuling LI Jianjin et al. |
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| Affiliation: | /LU Dejian,LIU Qiuling,LI Jianjin,et al. /Faculty of Forensic Medicine,Sun Yat-sen University of Medical Sciences,Guangzhou 510089 |
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| Abstract: | To investigate haplotype distribution of the Y-chromosome STRs (DYS19, DYS390 and DYS389 locus) in Han population in Guangdong area. The STRs were typed by poplymerase chain reaction followed by discontinuous PAGE system. Among 130 unrelated males, 81 different haplotypes were observed, 52 out of them were found only one time. The haplotype genetic diversity, discrimination power and non-father exclusion chance are 0. 9989, 0. 9824, 0. 9824, respectively. The high informative haplotypes make these STRs useful for the forensic individual identification and paternity testing. |
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| Keywords: | Y chromosome Haplotype Short tandem repeats (STR) Guangdong Han population |
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