模式翻转视诱发电位P100与视敏度的相关性

目的 通过研究不同程度视敏度障碍者模式翻转视诱发电位(pattern reversal visual evoked potentials,PRVEP)P100的特征,分析不同视角光刺激下与视敏度之间的相关性.方法 选用视敏度分别为0.2、0.4、0.6、0.8、1.0志愿者共100只眼,采用不同空间频率(8°到7.5＇...

Correlation of pattern reversal visual evoked potentials P100 with visual acuity

Objective To explore pattern reversal visual evoked potential（PRVEP） P100 components in the patients with different visual acuity and the correlation of P100 components with visual acuity using different visual simulation angles.Methods PRVEPs were recorded at Oz point in the patients（100 eyes） with different visual acuity including 0.2,0.4,0.6,0.8 and 1.0 and induced by pattern reversal visual simulation with the different spatial frequencies（check sizes： 8°-7.5′）.The latency and amplitude of components P100 were analyzed and statistical analysis was performed using SPSS 13.0 software.Results The latency and amplitude of P100 wave showed a curvilinear relationship with check sizes.With check size 1° simulation in 0.2 visual acuity group,the P100 latency reached to the minimum and the P100 amplitude showed peak value.Other groups displayed the best value with check size 30′.The P100 latency and amplitude showed a linear correlation with visual acuity.With the increase of visual acuity,the P100 wave latency decreased and the amplitude increased gradually.Regression models between visual acuity and the P100 wave latency and amplitude were also established.Conclusion The regression functions can be an objective and accurate method to evaluate the visual acuity based on the better simulation angles using PRVEP examination.