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犬组织中艾司唑仑在甲醛溶液中的稳定性
引用本文:Yuan JX,Wang YJ,Yun KM. 犬组织中艾司唑仑在甲醛溶液中的稳定性[J]. 法医学杂志, 2011, 27(2): 117-9, 124. DOI: 10.3969/j.issn.1004-5619.2011.02.009
作者姓名:Yuan JX  Wang YJ  Yun KM
作者单位:山西医科大学法医学院;
基金项目:山西省自然科学基金资助项目(2007011105); “十一五”国家科技支撑计划项目(2007BAK26B05)
摘    要:目的 研究甲醛溶液保存的生物样品中艾司唑仑的稳定性.方法 犬以艾司唑仑37.6mg/kg剂量灌胃,2h处死,解剖取其心、肝、肾、脑并分割为1g/份,分别放置于4%甲醛溶液中固定,用高效液相色谱法测定各组织及甲醛液中的艾司唑仑含量.结果 犬心、肝、肾、脑组织随着固定在甲醛溶液中时间的延长,组织及从组织溶解到甲醛溶液中的艾...

关 键 词:法医毒理学  艾司唑仑  甲醛  稳定性  

Stability of estazolam in dog tissues preserved in formaldehyde solution
Yuan Jiu-xi,Wang Yu-jin,Yun Ke-ming. Stability of estazolam in dog tissues preserved in formaldehyde solution[J]. Journal of Forensic Medicine, 2011, 27(2): 117-9, 124. DOI: 10.3969/j.issn.1004-5619.2011.02.009
Authors:Yuan Jiu-xi  Wang Yu-jin  Yun Ke-ming
Affiliation:YUAN Jiu-xi,WANG Yu-jin,YUN Ke-ming(School of Forensic Medicine,Shanxi Medical University,Taiyuan 030001,China)
Abstract:Objective To investigate the stability of estazolam in biological samples preserved in formaldehyde solution.Methods The dog was given intragastric administration of estazolam with a dose of 37.6 mg/kg and killed 2 h later.Heart,liver,kidney and brain of the dog were cut up into 1 g and preserved in 4% formaldehyde solution respectively.The content of estazolam in biological samples and formaldehyde solution were analyzed by HPLC at different times.Results The content of estazolam in heart,liver,kidney and ...
Keywords:forensic toxicology  estazolam  formaldehyde  stability  dogs  
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