| DGGE技术检测小核核糖核蛋白多肽N基因rs220030位点的多态性 |
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| 作者姓名： | Zhao Y Xu HM Zhao ZQ |
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| 作者单位： | 复旦大学上海医学院法医学系,上海,200032 |
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| 摘 要： | 目的 分析小核核糖核蛋白多肽N(small nuclear ribonucleoprotein polypeptide N,SNRPN)基因SNP位点rs220030在中国汉族人群中的基因结构特征及多态性,获得群体遗传学资料.方法 应用变性梯度凝胶电泳(denatu^ng gradient gel electropho...
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| 关 键 词： | 法医遗传学 多态性 单核苷酸 变性梯度凝胶电泳 rs220030 |
Polymorphism study of small nuclear ribonucleoprotein polypeptide N gene rs220030 by DGGE |
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| Zhao Y,Xu HM,Zhao ZQ.Polymorphism study of small nuclear ribonucleoprotein polypeptide N gene rs220030 by DGGE[J].Journal of Forensic Medicine,2011,27(3):186-188. |
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| Authors: | Zhao Yun Xu Hong-Mei Zhao Zi-Qin |
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| Institution: | ZHAO Yun,XU Hong-mei,ZHAO Zi-qin(Department of Forensic Medicine,Shanghai Medical College,Fudan University,Shanghai 200032,China) |
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| Abstract: | Objective To analyze the polymorphism of rs220030,a SNP which is located in the promoter region of small nuclear ribonucleoprotein polypeptide N(SNRPN) gene in the Chinese Han population and to obtain the data of population genetics.Methods The denaturing gradient gel electrophoresis(DGGE) method was applied to detect the polymorphism of rs220030 in 100 unrelated and healthy individuals from the Shanghai Han population.The genotyping result of this SNP was confirmed by TaqMan assay in some typical samples.R... |
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| Keywords: | forensic genetics polymorphism single nucleotide denaturing gradient gel electrophoresis rs220030 |
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