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米糠凝集素的部分特性及其抗新城疫病毒作用
引用本文:刘娜,刘利强,刘彦威,王斌.米糠凝集素的部分特性及其抗新城疫病毒作用[J].中国兽医科学,2007,37(8):709-713.
作者姓名:刘娜  刘利强  刘彦威  王斌
作者单位:河北工程大学,农学院,河北,邯郸,056021
摘    要:采用红细胞凝集试验和观察细胞病变(CPE)的方法分别研究了米糠凝集素的特性和抗病毒作用。结果显示,米糠凝集素能凝集鸡红细胞,促进新城疫病毒对红细胞的凝集,对热有一定的稳定性,耐酸碱;在体外,用米糠凝集素与新城疫病毒作用或用米糠凝集素预处理Vero细胞,均能抑制新城疫病毒在细胞上病变的形成。提示,米糠凝集素具有直接抗新城疫病毒和预防新城疫病毒感染的作用。

关 键 词:米糠凝集素  特性  新城疫病毒
文章编号:1673-4696(2007)08-0709-05
修稿时间:2007年1月26日

Some characteristics of bran lectin and its effect against Newcastle disease virus
LIU Na,LIU Li-qiang,LIU Yan-wei,WANG Bin.Some characteristics of bran lectin and its effect against Newcastle disease virus[J].Veterinary Science in China,2007,37(8):709-713.
Authors:LIU Na  LIU Li-qiang  LIU Yan-wei  WANG Bin
Abstract:Characteristics and anti-Newcastle disease virus(NDV) effect of bran lectin were investigated by hemagglutination test and observation of cytopathic effect.Bran lectin was able to agglutinate chicken erythrocyte,and promote hemagglutinating activity of NDV with resistance to heat,acid and alkali.Either pre-mixed bran lectin with NDV or with Vero cells for 1 hour before cell cultivation assay was able to inhibit cytopathic effect of NDV significantly.These results suggested that bran lectin had direct and preventive effect against NDV infection.
Keywords:bran lectin  characterization  Newcastle disease virus
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