Studying schizophrenia outside the psychiatric setting

Two groups of college students were identified using the MMPI as a screening device: those with normal profiles and those with schizophrenic profiles. All those with previous psychiatric treatment were eliminated. A third group of hospitalized schizophrenics was matched to the first two along lines of age, sex and socioeconomic status. The three groups were then studied via a semistructured interview and compared for the clinical features of hospitalized schizophrenics and for objective enironmental stresses. As predicted, a group of well-functioning, untreated schizophrenics was delineated. The usefulness of the MMPI as a screening device is clarified, and the question of the true prevalence of schizophrenia is discussed. Contrary to prediction, the well-functioning schizophrenics were similar to the hospitalized schizophrenics, not to the normal controls, with regard to objective environmental stresses. The possible meaning of this is discussed considering the concept of subjective environmental stresses.This research is in part supported by USPHS grants MH-18991, MH-19477-01, and State of Illinois 131-13-RD, State of Illinois 218-12-RD.This reasearch is part of an extensive program investigating schizophrenia which is being conducted jointly by the Psychosomatic and Psychatric Institute of Michael Reese Hospital, the Department of Psychiatry, Pritzker School of Medicine, the University of Chicago, and the Illinois State Psychiatric Institute.Received M.D. from Northwestern University. Served psychiatric residency at the Psychosomatic and Psychiatric Institute of Michael Reese Hospital. Main interest is in psychotherapy and psychodynamics of youth.