| Identifiler^TM系统在亲子鉴定中的应用评估 |
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| 引用本文： | 阙庭志,严品华,林源,柳燕,李莉. Identifiler^TM系统在亲子鉴定中的应用评估[J]. 法医学杂志, 2009, 25(3): 184-186. DOI: 10.3969/j.issn.1004-5619.2009.03.009 |
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| 作者姓名： | 阙庭志 严品华 林源 柳燕 李莉 |
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| 作者单位： | 司法部司法鉴定科学技术研究所上海市法医学重点实验室,上海,200063 |
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| 摘 要： | 目的评估Identifiler^TM系统15个短串联重复序列（STR）基因座在亲子鉴定中的检验能力。方法用Identifiler^TM系统检测3277例亲子鉴定案例，观测和分析该系统在亲子鉴定中的排除能力及基因突变率。结果累积非父排除率为0．999998827，累积个体识别能力为0．99999999999999998。3277例亲子鉴定中有2863例认定亲权关系，347例排除亲权关系；观察到65例中有1个STR基因座发生突变，2例中有2个STR基因座发生突变。结论Identifiler^TM体系应用于亲子鉴定是高效、可靠的。
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| 关 键 词： | 法医遗传学 亲子关系 短串联重复序列 IdentifilerTM系统 |
The Evaluation of Identifiler~(TM) System in Paternity Testing |
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| QUE Ting-zhi,YAN Pin-hua,LIN Yuan,LIU Yan,LI Li. The Evaluation of Identifiler~(TM) System in Paternity Testing[J]. Journal of Forensic Medicine, 2009, 25(3): 184-186. DOI: 10.3969/j.issn.1004-5619.2009.03.009 |
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| Authors: | QUE Ting-zhi YAN Pin-hua LIN Yuan LIU Yan LI Li |
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| Affiliation: | QUE Ting-zhi,YAN Pin-hua,LIN Yuan,LIU Yan,LI Li(Shanghai Key Laboratory of Forensic Medicine,Institute of Forensic Science,Ministry of Justice,P.R.China,Shanghai 200063,China) |
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| Abstract: | Objective To evaluate the power of IdentifilerTM System for paternity testing.Methods A total of 3 277 paternity testing cases were studied using IdentifilerTM System.The exclusion power and mutation rates of the IdentifilerTM System were analysed in the paternity testing.Results The cumulated power of exclusion was 0.999 998 827,and the cumulated discriminating power was 0.999 999 999 999 999 98,respectively.Of the 3 277 cases,paternity was confirmed in 2 863,but excluded in 347.Among this paternity testin... |
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| Keywords: | forensic genetics paternity testing short tandem repeat IdentifilerTM System |
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