运用神经行为测试系统评价酒后行为功能的可行性研究

目的研究运用神经行为测试系统评价酒后行为功能的可行性。方法采用汉化第三版计算机化神经行为评价系统(NES-C3),通过自身对照的方式,对49名饮酒者进行神经行为功能的测试,并与步行回转试验进行比较。结果心算、视觉保留、线条判断和数字筛选均在酒后0.5￣2.5h的时间点上能力指数有所下降,视简单反应时能力指数下降则延续至酒后5.5h;步行回转在酒后0.5￣2.5h间有阳性案例。血中酒精质量浓度在0.50mg/mL以上,视觉保留、线条判断及视简单反应时的能力指数有明显下降;血中酒精质量浓度在0.80mg/mL以上,心算和数字筛选的能力指数有明显下降。步行回转实验的阳性人数在血中酒精质量浓度0.50mg/mL以上有明显增加。结论计算机化神经行为评价系统作为一个定量指标,可反应酒精质量浓度与神经行为功能的关系,且比步行回转试验更客观、更灵敏。

The Feasibility Researches on the Evaluation of Neurobehavioral Functions after Drinking with Neurobehavioral Evaluation System

Objective To research the feasibility of measuring neurobehavioral function after drinking with neurobehavioral evaluation system -chinese(NES-C3). Methods Forty nine volunteers before and after drinking were tested with NES-C3 and walking around test. Results It was showed that the neurobehavioral ability index(NAI) of mental arithmetic, benton visual retention, length discrimination and digit cancel declined during 0.5~ 2.5 hours after drinking, the NAI of simple visual reaction time declined during 0.5~5.5 hours after drinking. There were 26 positive cases in 332 cases during 0.5~2.5 hours after drinking in the walking around test. the NAI of benton visual retention, length discrimination and simple visual reaction time declined obviously when alcohol concentration exceeded 0.50mg/mL, the NAI of mental arithmetic and digit cancel declined obviously when alcohol concentration exceeded 0.80mg/mL. There were 25 positive cases in all cases in the walking around test when alcohol concentration exceeded 0.50mg/mL. Conclusion The NES-C3 can respond the relation of alcohol concentration and neurobehavioral function. The NES-C3 is more sensitive and impersonal than walking around test.