GC-MS检测新型策划毒品K3

目的基于气相色谱-质谱（GC-MS）检测结合特殊质谱库信息检索建立新型策划毒品的鉴定方法。方法未知样品用甲醇超声溶解,吸取上清液采用气相色谱-质谱（GC-MS）联用仪检测。结果测得A组分（t R=19.47min）的质谱特征碎片峰（m/z）信息为215.1（基峰）、144.9、294.1、337.1和365.1,B组分（tR=23.29min）的质谱特征碎片峰（m/z）信息为359.1（基峰）、127.1、144.0、155.0、232.1、284.1和342.0。经美国缉毒署毒品分析谱库检索获得的信息资料,鉴定为新型策划毒品＂K3＂,其主要组分为＂AKB48＂和＂AM2201＂,此类化合物具有大麻类似精神活性,归属合成大麻素。结论本方法可用于新型策划毒品组分的鉴定。

Identification of the New Type Drug K3 by GC-MS

Objective To establish a gas chromatography-mass spectrometry （GC-MS） method with special mass spectra library searching for the identification of the new-type drugs. Method The sample extraction was performed with methanol in ultrason- ic bath. And the supernatant was injected into GC-MS system. Results Component A （tR = 19.47min） has characteristic frag- ment ion peaks at m/z 215.1 （base peak）, 144.9, 294. l, 337.1 and 365.1. Component B （tR =23.29min） has characteristic fragment ion peaks at m/z 359.1 （base peak）, 127.1, 144.0, 155.0, 232.1, 284.1 and 342.0. According to the information searched from U.S. Drug Enforcement Administration mass spectra library, this drug is identified as new-type drug ＂K3＂. Its main components are ＂AKB48＂ and ＂AM2201＂. The drug has similar psychoactive activity to marijuana and belongs to synthet- ic cannabinoids. Conclusion The method can be used for identifvin~ comoonents of the new-tvoe dru~s.