大鼠脑挫伤后脑组织β-APP表达的研究

目的观察大鼠实验性脑挫伤后CNS内β-APP蛋白表达时空性规律。方法采用自由落体撞击法致大鼠脑挫伤模型,用免疫组化技术观察伤后β-APP蛋白在不同时间(0.5h、2h、6h、12h、24h、3d、7d、14d)的表达情况,并用计算机图像分析技术作定量统计分析。结果(1)皮质内β-APP蛋白在伤后表达呈一定波动性,0.5h表达明显增加后,逐渐下降,12h降至最低,低于对照组,随后再次表达增加,3d达高峰;(2)伤后24h海马区β-APP表达开始逐渐下降,3d降至最低,14d回到对照组水平;(3)齿状回(DG)内β-APP蛋白在伤后12h低于对照组。结论实验性脑挫伤后皮质β-APP表达时序性规律可为脑损伤时间推断提供一个新的参考指标,但海马区及DGβ-APP变化规律在脑损伤时间推断方面价值不大。     

一种收集衣服上脱落细胞的新方法

目的建立一种生物脱落细胞的微量提取新方法。方法利用一套自制的“生物细胞提取仪”无损提取衣物等载体上的人体脱落细胞,采用Chelex-100法提取DNA,用不同的试剂盒进行STR复合扩增检验。结果10例检材都得到16个基因座成功分型。结论用该方法提取微量细胞DNA,可获得满意的DNA分型。     

复合扩增mtDNA-HVI和Cyt b片段鉴定混合血痕种属

目的探讨mtDNA-HVI和Cyt b片段复合扩增法鉴定人与动物混合血痕种属的应用价值。方法用chelex-100法从人、牛、猪、狗、兔、鱼、鸡和鼠血痕中提取DNA,复合扩增mtDNA-HVI片段和Cyt b片段,琼脂糖凝胶电泳检测。结果人类在mtDNA-HVI区和Cyt b区分别出现279bp和358bp各一条带,且279bp条带亮于358bp;动物均只有358bp一条带。人与7种动物血痕的检测灵敏度均为3.13ng。检测人与动物混合DNA,灵敏度仍为3.13ng,但358bp条带亮于279bp条带。结论当358bp带明显强于279bp带时,提示检材为人与动物的混合。     

8例利多卡因过敏性休克死的血药浓度分析

目的研究利多卡因过敏性休克死者利多卡因血药浓度及其与死因的关系。方法采用高效液相色谱法(HPLC),分别对使用利多卡因麻醉术中各项指标均正常的8例术中因利多卡因过敏性休克死者的血液和11例顺利完成手术患者的血液进行利多卡因浓度的检测,对比分析两者结果。结果 8例死者利多卡因血药浓度(1．61mg± 0．45mg／L)低于11例正常患者利多卡因血药浓度(2．44mg±0．47mg／L)。结论利多卡因过敏性休克死者血药浓度在正常值范围内,与发生过敏性休克致死无关。     

依据Marshall和Hoare的数学模型推断死亡时间的新方法

在对Marshall和Hoare的尸体直肠冷却数学模型做进一步研究的基础上,建立了一种适于在环境温度为3°～24℃时推定死亡时间的新方法。用本法检测34具机械性损伤尸体与国内的两种计算方法比较,效果较优,于死后15小时内进行168次计算,误差在±1小时内的为57.1％～77.7％,它能较好地反映个体差异,因而比Marshall等的原方法更能客观地反映直肠冷却规律。     

生物检材中氰化物浓度与保存时间关系研究

通过动物试验，用荧光光度法测定生物检材中氰化物浓度，研究了氰化物浓度与保存时间关系。结果表明，染毒血液高体120h内，氰化物浓度呈平缓直线上升；120h至168h之间呈指数下降；染毒肝脏检材在168h内呈直线上升，建立了线性方程。     

试论“肾主大便”

According to viscera-state doctrine and clinical practice of distinguished physicians of the past, Kidney-yang and Kidn e y-yin not only directly affect the formation of stool but also indirectly affect that by means of warming and nourishing the spleen and stomach, generating between the lung and kidney, the kidney and bladder sharing a paired relationship in physiology. In pathology, deficiency of Kidney-yang re su 1 tsin diarrhea, insufficiency of Kidney-yang or Kidney-yin resul tsin constipation. Being directed at pathogenesis, the methods of treatment should be warming the Kidney to stop diarrhea, warming the Kidney to relax the bowels, nourishing the Kidney to keep the bowels open and so on. In addition, this article still probes into some part of the mechanism of "Kidney Controls Stool" .     

C. Reviews: general

THE HISTORY OF AL‐TABARI. VOL. III: THE CHILDREN OF ISRAEL. Translated by WILLIAM M. BRINNER. Albany, N.Y., SUNY Press, 1991. xii, 194 pp. $44.00 (hb), $14.95 (pb).

THE HISTORY OF AL‐TABARI. VOL. XXXIII: STORM AND STRESS ALONG THE NORTHERN FRONTIERS OF THE ‘ABBASID CALIPHATE. Translated by C.E. BOSWORTH. Albany, N.Y., SUNY Press, 1991. xix, 239 pp. $57.50 (hb), $18.95 (pb).

THE AWAKENING OF PERSIA: THE REIGN OF NASR AL‐DIN SHAH 1848–1896. By A.J. ABRAHAM. USA, Vande Vere Publishing, 1992. 64pp. $18.95.

THE EMERGENCE OF KURDISH NATIONALISM AND THE SHAIKH SAID REBELLION, 1880–1925. By ROBERT OLSON. Austin, University of Texas Press, 1992.

THE ARAB BUREAU: BRITISH POLICY IN THE MIDDLE EAST, 1916–1920. By BRUCE WESTRATE. University Park, PA, Pennsylvania State University Press, 1992. xvi, 240 pp. $35.

DIE TÜRKEI UND ÄGYPTEN IN DER WELTWIRTSCHAFTSKRISE 1929–1933. By CAMILLA DAWLETSCHIN‐LINDER. (Studien zur modernen Geschichte, 40). Stuttgart, Franz Steiner Verlag, 1989. xviii, 187 pp. 20 tables, 6 diagrams. DM 68‐.

EGYPT FROM INDEPENDENCE TO REVOLUTION, 1919–1952. By SELMA BOTMAN. Syracuse, Syracuse University Press, 1991.

EXPULSION OF THE PALESTINIANS: THE CONCEPT OF ‘TRANSFER’ IN ZIONIST POLITICAL THOUGHT 1882–1948. By NUR MASALHA. Washington, DC, Institute for Palestine Studies, 1992. iii, 235pp. $24.95 (hb), $11.95 (pb).

TRANSITION TO SELF‐GOVERNMENT: PRACTICAL STEPS TOWARD ISRAELI‐PALESTINIAN PEACE. Report of a study group convened by the American Academy of Arts and Sciences, ANN MOSELY LESCH, principal author. Indiana University Press, 1993. 160pp. £22.50 (hb), £9.99 (pb).

GREATER SYRIA: THE HISTORY OF AN AMBITION. By DANIEL PIPES. New York and Oxford, Oxford University Press, 1990. viii, 240pp.

IBN SAUD: FOUNDER OF A KINGDOM. By LESLIE McLOUGHLIN. Basingstoke, Macmillan in association with St Antony's College, Oxford, 1993. 240pp. £40.00.

THE DESPAIRING DEVELOPER: DIARY OF AN AID WORKER IN THE MIDDLE EAST. By TIMOTHY MORRIS. London, Tauris, 1991.

A MODERN CULTURAL HISTORY OF BAHRAIN. By SAMI A. HANNA. Bahrain, National Council for Culture Arts and Literature, 1991. 107pp.

THE ECONOMIC CONSEQUENCES OF THE GULF WAR. By KAMRAN MOFID. London, Routledge, 1990. xxiv, 177pp.

EARLY ARABIC POETRY: MARATHI AND SU'LUK POEMS, Vol. 1. Edition, translation, and commentary by ALAN JONES. (Oxford Oriental Institute Monographs, 14.) Reading, Ithaca Press, 1992. ix, 270 pp. Map. £25.00.

RELIGION, LEARNING AND SCIENCE IN THE ‘ABBASID PERIOD. Edited by M.J.L. YOUNG, J.D. LATHAM and R.B. SERJEANT. (The Cambridge History of Arabic Literature.) Cambridge, Cambridge University Press, 1991. xxi, 587pp. £ 60.00 (hb).

THREE SHADOW PLAYS. By MUHAMMAD IBN DANIYAL. Edited by PAUL KAHLE. Critical apparatus by DEREK HOPWOOD. Introductory Essay by MUSTAFA BADAWI. (E.J.W. Gibb Memorial, New Series, 32.) Cambridge and Warminster, Gibb Memorial Trust/Aris and Phillips, 1992. 154pp. in Arabic and 30pp. in English. £12.00.

GENRE AND LANGUAGE IN MODERN ARABIC LITERATURE. By SASSON SOMEKH. Wiesbaden, Harrassowittz, 1991.

DER ARABISCHE DIALEKT DER JUDEN VON ‘AQRA UND ARBIL (Semitica Viva, 5.) By OTTO JASTROW. Wiesbaden, Harrassowitz, 1990. 438pp. DM 112.‐

1 For technical reasons, the symbol ‘e’ has been substituted for the ‘inverted e’ of the original throughout this review. [—Ed.]

WADAAN: REINFORCING READING/WRITING/FIRST LEVEL ARABIC COURSE, Vol.4. By DIONISIUS A. AGIUS, and PARWEEN N. ARIF. Leeds, University of Leeds, 1991. 65 pp.

HAYYAN BINA: KITAB AL‐TAMARIN. DRILLS/FIRST LEVEL ARABIC COURSE, Vol.5. By DIONISIUS A. AGIUS. Leeds, University of Leeds, 1991. 111 pp.

MUGHAMARAT ‘AJIBA FI QISAS MUFIDA: THIRD LEVEL ARABIC COURSE BOOK 1. By PARWEEN N. ARIF and DIONISIUS A. AGIUS. Leeds, University of Leeds, 1991. 64 pp.

UNVEILING ISLAM. By ROGER DU PASQUIER. Cambridge, Islamic Texts Society, 1992. viii, 157pp. £6.95.

CULTURAL SCHIZOPHRENIA. By DARYUSH SHAYEGAN. London, Saqi Books, 1992. vii, 188pp.     

鼻骨骨折螺旋CT3D成像与X线片对比研究

目的 评价螺旋CT扫描三维重建成像与X线摄片对比对鼻骨骨折法医学鉴定的价值。方法 使用SOMATOM BALANCE 1s螺旋CT机，对32例复杂鼻部外伤者2mm／2mm扫描，常规进行最大密度投影法(MIP)、多平面重建(MPR)、表面覆盖法(SSD)、容积成像(VR)方式。全貌显示受伤鼻骨骨折影像，并与常规鼻骨摄片比较。结果 螺旋CT三维成像纠正3例X线照片的假阳性和6例诊断骨折类型不准确。结论 螺旋CT三维重建对诊断复杂鼻骨骨折块数目、移位，以及骨折类型优于X线摄片。