Pseudolaminar necrosis in cyanide intoxication: a neuropathology case report

We describe the gross and microscopic neuropathological changes in the brain of a 17-year-old male who died 4 days after being poisoned with cyanide. Previous reports indicate that following cyanide intoxication, the brain develops diffuse hypoxic/ischemic changes, predominantly of the basal ganglia. The case we describe here had similar features but in addition showed striking laminar necrosis of the cerebral cortex. This finding in cyanide poisoning has been previously demonstrated by neuroimaging, but not pathologically.     

Y-chromosome STR haplotypes in Somalis

A total of 201 males from Somalia were typed for the Y-chromosome STRs DYS19, DYS385a/b, DYS389-I, DYS389-II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438 and DYS439 with the PowerPlex Y kit (Promega). A total of 96 different haplotypes were observed and the haplotype diversity was 0.9715. The number of unique haplotypes was 71 while the most common haplotype was observed 24 times.     

Mitochondrial DNA error prophylaxis: assessing the causes of errors in the GEP'02-03 proficiency testing trial

A qualitative and quantitative analytical method was developed and validated for the determination of 49 licit and illicit drugs in oral fluid. Small oral fluid samples, volume 1mL, were collected from volunteers using a modified Omni-Sal device and the analytes were extracted from an oral fluid/buffer mixture using a single Bond Elut Certify solid phase extraction cartridge. Liquid chromatography-tandem mass spectrometry (LC-MS-MS) and gas chromatography-repetitive full scan mass spectrometry (GC-MS) were used in parallel to analyze the extracts for the targeted drugs. Extracts were analyzed by GC-MS in their underivatized form and as their pentafluoropropionyl derivatives. Deuterated internal standards were used for quantification of drugs of abuse by LC-MS-MS to minimize matrix effects. Methadone-d(9) and tumoxetine were used as the internal standards for quantification of non-derivatized and derivatized analytes respectively by GC-MS. Linearity was demonstrated over the range 5-200 ng/mL and limits of detection were less than 4 ng/mL for each drug analyzed. The method demonstrated acceptable recoveries for most of the analytes and good intra- and inter-day precision. Acquisition of data by repetitive full scan GC-MS allows the addition of further analytes to the target menu.     

Y-chromosome STR haplotypes in Danes

A total of 185 unrelated Danish males were typed for the Y-chromosome STRs DYS19, DYS385a/b, DYS389-I, DYS389-II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438 and DYS439 using the kits PowerPlex Y (Promega), ReliaGene Y-Plex 6 and ReliaGene Y-Plex 5 (Reliagene Technologies). A total of 163 different haplotypes were observed and among these, 144 haplotypes were unique. The gene diversity was 0.9985. In DYS392, a variant allele migrating as a 10.2 allele was observed. Sequencing of the allele showed a deletion upstream the repeated area.     

欠发达地区树立和落实科学发展观促进跨越式发展的思考

欠发达地区经济发展的实现过程,应该是经济与社会、人与自然统筹兼顾、全面进步与协调发展的过程.实施跨越式发展与"以人为本,全面、协调、可持续发展"的科学发展观有机统一的发展道路是欠发达地区的理性选择.     

探索“两课”教学与学管工作一体化的新模式

加强学生思想政治教育势在必行。我校思想政治教育存在"两课"教学与学生思想实际脱节,学管工作方法滞后,与学生沟通少等问题。构建思想政治教育模式的具体做法包括:实行思想政治教育辅导员制,采取观察法、调查法、反馈法、实践法等。     

Nine autosomal STRs genotype profiles in a sample from Córdoba (Argentina)

Nine STRs loci have been typed in a sample from Córdoba (Argentina).     

Y-chromosome STR haplotypes in Córdoba (Argentina)

Eight Y-chromosome STRs were investigated in a male population sample from Córdoba region (Argentina). Complete Y-chromosomal STRs haplotypes were obtained in 100 individuals, among which 91 different haplotypes were observed. The most common haplotype was shared by 4% of the sample, while 86 haplotypes were unique. The gene diversity was 0.9875 and the discrimination capacity was 0.8600. The combined polymorphism provides a powerful discrimination tool for routine forensic applications.     

现代诉讼的法理性透视

现代社会的诉讼制度设计根据社会冲突的性质可主要划分为三种类型。即民事诉讼制度、刑事诉讼制度和行政诉讼制度。这三大诉讼在程序设计上有着共通的法理 ,即公正与衡平。文章从程序结构法理以及程序运作法理这两个方面对此进行了论述。随后 ,本文通过对诉讼中引入“合意机制”的思考 ,对现代诉讼的价值导向进行了反思 ,指出弘扬个体自治的深远意义。     

浅谈唐甄"治民必先治官"的思想及借鉴意义

唐甄是清朝著名的思想家,著有<潜书>,思想内容极其丰富,特别是其中的<柅政篇>,提出了"治民必先治官"的思想及治官的办法,在当前仍有一定的借鉴意义.