慢性阿片依赖者在戒断阶段细胞免疫功能的研究

为科学地鉴定、预防毒品相关死亡提供一定的实验证据，采用免疫组化、细胞培养、核素掺入、ELISA等方法，研究26例用药模式相近的慢性阿片依赖者在戒断阶段的细胞免疫功能，并与健康对照组进行统计比较。结果表明：慢性阿片依赖者戒断期CD＋4细胞数目减少（30．40±9．45％，P＜0．05），CD＋4／CD＋8比例降低（1．27±0．19，P＜0．01）；PBMC合成DNA的能力下降（SI＝8．62±3．20，P＜0．01），产生IL－2的水平降低（23．78±8．77，P＜0．06）和产生IL－6的能力呈降低趋势（468．81±196．40，P＞0．05）；血清中免疫抑制性因子sIL－2R水平显著升高（566．33±265．50，P＜0．01）。慢性阿片依赖者在戒断阶段有多种免疫参数紊乱，细胞免疫功能低下。     

Demirjian法在推断上海汉族青少年生活年龄中的应用

目的研究Demirjian法推断上海汉族青少年生活年龄的适用性。方法收集上海市第九人民医院符合纳入标准的年龄在11～20周岁的汉族青少年口腔曲面全景片501例．其中男性168例．女性333例。按照Demirjian法进行牙龄推断,并对生活年龄与Demirjian法推断的牙龄进行配对t检验：通过单因素数学模型探索两者之间的关系。结果直接应用Demirjian方法推断上海汉族青少年牙龄时．其推断的牙龄与实际生活年龄之间存在差异。通过建立牙龄推断的单因素数学模型。并将其推断的年龄与实际生活年龄进行配对t检验,结果显示男性12～16周岁（不含16周岁）、女性13～14周岁（不含14周岁）和15～17周岁（不合17周岁）年龄段无统计学意义（P〉0．05）,并且有81．04％的样本推断误差小于1岁。结论本研究有望成为推断上海地区汉族青少年生活年龄的有效方法,但不适合17周岁以上青少年人群。     

中国5城市儿童青少年手腕骨发育差异对年龄推测影响

目的探讨中国5城市儿童青少年手腕骨发育差异对年龄推测的影响。方法收集2005年中国上海、广州、温州、大连、石家庄11635名（男5971,女5664）汉族正常儿童青少年手腕部骨X线片,按RUS—CHN法标准评价受试者手腕骨骨龄,比较各城市儿童青少年的骨龄差异。结果广州男在8岁以下以及温州男9～12岁骨发育分别延迟0．14～0．19岁和0．13～0．17岁（P〈0．05）,上海男在7～15岁之间骨发育提前0．14～0．32岁（P〈0．05）。大连女在12岁以下、石家庄女在8岁以下骨发育分别延迟0．15～0．31岁和0．18～0．31岁（P〈0．05）;广州女在5～8岁骨发育延迟0．11～0．22岁（P〈0．05）;而上海女在8～9岁骨发育提前0．12～0．13岁（P〈0．05）。结论中国5城市儿童青少年手腕骨发育在不同年龄段存在不同程度的差异。     

河南省安阳市6-15周岁汉族人牙龄的研究

目的建立利用牙齿钙化程度推断未成年人年龄的方法。方法选取河南省安阳市1575名（男性900名,女性675名）6～15周岁人群的全口曲面断层影像片,依照牙齿钙化分级标准对下颌恒牙钙化程度进行评分分级;所得数据经SPSS13．0软件统计分析,建立根据牙齿钙化程度推断年龄的方程;采用拟合优度检验、模型方差分析、回归系数检验和共线性诊断、残差分析对方程的合理性进行检验及盲测。结果下颌同名牙间钙化分级评分值无统计学差异（P〉0．05）,而下颌同名牙性别间钙化评分值在部分年龄组存在差异（P〈0．05）;下颌恒牙的钙化程度与年龄相关系数r均大于0．7;所建方程模型调整决定系数均大于0．8,估计值标准误男性为0．92岁至1．04岁、女性为0．92岁至1．00岁;推测年龄与真实年龄的平均误差男性为0．433±0．288岁、女性为0．502±0．297岁。结论本研究建立的方法在推断相关地区、相关年龄段人群的年龄推断中有较好的应用前景。     

国人头面部软组织厚度的MRI测量

用磁共振成像（MRI）方法对498例（男274，女224）中国汉族人头面部31个标志点（正中线16，侧面15）的软组织厚度分7个年龄组进行了测量。结果表明，国人（汉族）头面部软组织厚度一般随年龄增长而增厚，大约在45～59岁最厚，60岁以后又开始变薄；男女性头面部软组织厚度有性别差异，在大多数测量点男厚于女，在19个测量点中有显著性差异（0．01＜P＜0．05）。个体因素对颜面上下部软组织厚度有不同影响，下面部软组织厚度受个体因素影响较上面部大。     

性自我防卫能力评定量表在非精神发育迟滞精神障碍患者中的适用性

目的探讨性自我防卫能力评定量表在非精神发育迟滞精神障碍患者中的适用性。方法收集性自我防卫能力评定案例87例,由经过培训的人员按照精神障碍者性自我防卫能力评定量表（CapacityofSexualSelf—defenseAssessmentScale,CSSAS）进行评分,并与专家鉴定意见进行比较。结果按照专家鉴定意见分组,有性自我防卫能力组、性自我防卫能力削弱组和无性自我防卫能力组的CSSAS评分分别为5．97±5．83、32．22±10．15、61．60±13．02,3组间的差异具有统计学意义（P〈O．01）。量表各条目得分与总分的相关系数为0．59～0．91,全量表的Cronbachd系数为0．96,拆半信度Cronbach理系数分别为0．94和0．91,两部分的相关系数为0．94。按照原始界值分,量表评定结果与专家鉴定意见的Kappa值为0．32（P〈0．01）,重新划定界值分后．两者的Kappa值为0．84（P〈0．01）。因子分析共提取2个因子,方差解释率分别为46．15％和28．93％,判别函数回代94．30％的样本被正确划分。结论CSSAS可应用于非精神发育迟滞精神障碍患者的性自我防卫能力评定,但应重新修订界值分和因子的权重。     

青少年手腕骨骨龄与生活年龄的差异观察

目的比较以不同骨龄标准所评价的青少年手腕骨骨龄与生活年龄的差异,观察生长发育长期变化对青少年年龄推测的影响。方法从中国5座大中城市抽取11464名（男5873,女5591）3～18岁汉族正常青少年儿童,并另随机抽取950名（男516,女434）12～18岁骨发育正常的汉族青少年作为验证样本。按CHN法和RC法骨龄标准评价手腕部X线片骨龄,并对不同方法评价的骨龄及生活年龄进行统计学分析。结果各年龄组CHN法骨龄中位数大于RC骨龄,其差异具有显著性意义（P〈0．05）。验证样本中,在男12—16．5岁、女12～14．5岁之间,CHN骨龄减生活年龄之差值分别为0．35—1．00岁和0．57～1．16岁（P〈0．01）;RC骨龄减生活年龄的差值分别为-0．26—0．23岁和-0．27～0．06岁（P〉0．05）。在男17～18岁、女15～17岁之间,CHN骨龄减生活年龄的差值分别为-0．52～-1．05岁和-0．16～-1．13岁（P〈0．05）,RC骨龄减生活年龄的差值分别为-0．35～-0．48岁和-0．22～-0．79岁（P〈0．05）。结论CHN法骨龄高于生活年龄,在大部分年龄组RC骨龄与生活年龄基本一致。     

数字X线摄影测量活体脊柱胸段推算身高

目的建立人脊柱胸段长度推算身高的方法。方法应用数字X线摄影技术（DR）摄制514例中国四川汉族人群的胸部DR片，测其脊柱胸段长度，同时准确测量被研究者身高，对测量获得的脊柱胸段长度与身高数据分组进行线性回归分析，建立胸段长度推算身高的回归方程。结果建立了混合组、男性组、女性组、20—45岁男性组、大于45岁男性组、20～45岁女性组和大于45岁女性组7个回归方程，经显著性检验，均有统计学意义（P〈0．01），复相关系数（R）范围0．834～0．624，回归系数（b）范围0．259～0．389，回归方程估计值的标准误在3．88～4．72cm范围内。结论利用人类脊柱胸段长度推算身高的方法在法医学个人识别中具有重要价值。     

四川汉族青少年面部中线软组织厚度的数字X线测量

目的 测量四川汉族青少年（8—20岁）人群面部中线软组织厚度，探讨其生长发育变化规律，为法医人类学的面部重建提供的基础数据。方法 选取974例（男496，女478）头颅侧位数字X线片，分13个年龄段（8—20岁）。选择面部10个标志点的软组织厚度测量，并进行描述性统计学分析。结果 四川汉族青少年人群面部10个标志点的中线软组织平均厚度，在青少年阶段大多数测量标志点随年龄增长而增厚；男女性面部中线软组织厚度统计学分析存在性别差异（P〈0．05），在15岁之后差异增大，且LU点显著差异性在9-20岁之间均存在（P〈0．01）。结论 四川汉族青少年面部中线软组织厚度有随年龄增长而增厚的档势．男女面部软组织厚度存在性别差异。     

中空性皮下出血宽度与致伤木棒直径的相关性

目的观察不同直径和不同打击力度的圆柱形木棒对垂直方向打击皮肤所形成的中空性皮下出血形态的相关性。方法采用生物力学击打装置,使用5种不同直径（2.0～4.0cm）木棒,从零递增击打力度（0～2300N）,对活体乳猪背部皮肤进行打击,观察乳猪背部皮肤中空性皮下出血分布范围、色泽及形态特征,并采用SPSS 13．0统计软件对所得数据进行分析。结果中空性皮下出血出现的最小打击力度阈值（230N）,随打击工具直径的增大而阈值增大（230～810N）;同一直径的木棒在不同击打力度下所形成的中空性皮下出血总宽度及中空宽度均没有统计学差异（P〉0.05）。中空性皮下出血的范围随木棒直径的增大而增大（R2=0．953,P〈0．01）;皮下出血总宽度及中空宽度与打击物直径,存在较好的正相关性（R2=0．797,P〈0．01）,符合一元线性回归方程模型。结论本研究可望用于推断垂直打击造成中空性皮下出血的木棒直径的大小,为钝器致伤工具的判断提供初步的理论依据。     

Delinquent Behaviour,Psychosomatic Symptoms and the Idea of 'Healthy Delinquency'

This study examines the association between self-reported delinquent behaviour and psychosomatic symptoms in a nationally representative sample of 15-16-year old Finnish adolescents. Some theorists have suggested that psychosomatic symptoms are related to inability to break culturally given norms. If this is so, delinquents should have less symptoms than non-delinquents. To assess this idea, two hypotheses are formulated: delinquency is associated with decreased symptoms (the 'hydraulic' hypothesis), or delinquency is associated with increased symptoms (the 'stress' hypothesis). In support of the second hypothesis, the results indicate that delinquency and psychosomatic symptoms are positively associated. The effect of delinquency on symptoms is robust in the presence of a number of control variables. The findings are discussed i.a. from the point of view of increasing research interest in the positive effects of delinquency. While positive effects are likely to exist in specific contexts, delinquency as such does not lead to a reduction of psychosomatic symptoms.     

未成年人刑事案件社会调查制度论纲

未成年人一般具有极强可塑性。如果法官的判决是有利于其改过自新的,则此种基于刑罚个别化的判决对该未成年人而言,无疑是再社会化和预防犯罪的良方。蕴涵人格调查的社会调查制度应当是形成前述判决的基础。在我国少年司法制度尚不完备的当下,应以该制度的正当性为基点展开研究,以期运用于少年刑事司法实践。     

VIOLENT DELINQUENTS AND URBAN YOUTHS*

Violent juvenile crime is disproportionately concentrated in urban neighborhoods, and accordingly an understanding of the sources of serious delinquency is con founded by components of urbanism. These milieus usually have high rates of absolute poverty and relative economic deprivation, as well as weak social institutions. The persistent findings of delinquent peer contributions to delinquency have yet to be tested under conditions where social class and milieu effects are controlled. There is little empirical evidence to determine how adolescents in high-crime neighborhoods avoid delinquency despite frequent contact with delinquent peers. The differences between violent delinquents and other youths from comparable neighborhoods are little understood. This study contrasts a sample of chronically violent male juvenile offenders with the general male adolescent population (students and school dropouts) from inner-city neighborhoods in four cities. Violent delinquents differ from other male adolescents in inner cities in their attachments to school, their perceptions of school safety, their associations with officially delinquent peers, their perceptions of weak maternal authority, and the extent to which they have been victims of crime. Peer delinquency and drug“problems” predict the prevalence of three delinquency offense types for both violent offenders and neighborhood youths. Among violent delinquents, there appear to be different explanatory patterns, with one type better described by internal controls (locus of control), a developmental measure. Overall, there is strong support for integrated theory including control and learning components, and similar associations exist among inner-city youths as in the general adolescent male population. Despite the generally elevated rates of delinquency in inner cities, the explanations of serious and violent delinquency appear the same when subjects are sampled at the extremes of the distribution of behavior.     

Gender and Race Differences in Delinquent Careers

Abstract Studies of delinquent careers have often tracked only male offenders, and have almost always failed to explore the interaction of race and gender in delinquency. This study tracks a cohort of youth whose first referral to juvenile court was in 1980, and explores the role played by both race and gender in official delinquent careers. Findings reveal that both race and gender play a significant role in official delinquency. Looking first at female delinquency, this research finds that white and nonwhite females do not differ significantly in the types of offenses they commit. Moreover, if girls are “chronic” delinquents, their offenses are most often trivial rather than serious. With males, racial differences emerge in both seriousness and chronic nature of delinquency. Nonwhite males in this cohort are more likely to be referred for personal offenses and less likely to be referred for public order and victimless offenses. Nonwhite males are also significantly more likely to become recidivists, and to have more seriously delinquent careers. This article discusses the implications of these findings, particularly with reference to the “convergence theory” of delinquency, which suggests that race plays a stronger role than gender in female delinquency. Finally, the article considers the policy implications of the current range of definitions of “chronic” delinquency.     

SELF-REPORTED DELINQUENCY AND A COMBINED DELINQUENCY SERIOUSNESS SCALE BASED ON BOYS,MOTHERS, AND TEACHERS: CONCURRENT AND PREDICTIVE VALIDITY FOR AFRICAN-AMERICANS AND CAUCASIANS*

The Pittsburgh Youth Study is a prospective longitudinal survey of three samples of Pittsburgh boys (each containing about 500 boys) initially studied in first, fourth, and seventh grades. The first two data collection waves yielded self-reported delinquency and combined delinquency seriousness scores (the combined scores based on information from boy, mother, and teacher) for the middle sample (up to an average age of 10.7 years) and oldest sample (up to an average age of 13.9 years). These scores were compared with records of petitions to the Allegheny County Juvenile Court for delinquency offenses before and up to six years after the assessments. The area under the ROC curve was used as a measure of validity. Concurrent validity was higher than predictive validity. The combined scale had similar concurrent validity but greater predictive validity than the self-report scale, and the combined scale also identified a greater number of boys as serious delinquents. Concurrent validity for admitting offenses was higher for Caucasians, but concurrent validity for admitting arrests was higher for African-Americans. There were no consistent ethnic differences in predictive validity. There was an increase in predictive validity, for both African-Americans and Caucasians, by combining self-report data with information from other sources. Afrer controlling for delinquency measures, African-Americans were more likely than Caucasians to be petitioned in the future, but not in the past. In this research, ethnic differences in official delinquency were partly attributable to ethnic differences in delinquent behavior and were not attributable to differential ethnic attrition or differential ethnic validity of measures of delinquent behavior.     

Isolation and normlessness: attitudinal comparisons of adolescent sex offenders, juvenile offenders, and nondelinquents

The authors explored attitudinal differences among adolescent male sex offenders, juvenile delinquents, and nondelinquent youth based on three variables drawn from integrated delinquency theory: conventional attitudes, normlessness, and social isolation. Consistent with previous juvenile delinquency studies, the results indicate no differences among the three groups on conventional attitudes. With respect to normlessness, both the sex offenders and juvenile delinquent groups demonstrated more school normlessness than did nondelinquent youths, and adolescent sex offenders showed greater peer normlessness than did either nondelinquent youths or juvenile delinquents. Examination of perceived social isolation among the three groups indicates that sex offenders consistently perceived themselves as more isolated than other youths with their families, in their school, and among their peers. These results suggest that interpersonal factors, in addition to a lack of social controls and normlessness, are associated with sexually inappropriate behavior.     

Analysis of cognitive inhibition and flexibility in juvenile delinquents

Executive functions are still developing during adolescence. It is important to analyse if juvenile delinquency is related to a delay in the development of these functions. The objective of this study was to analyse cognitive inhibition and flexibility, two components of executive functions, in juvenile delinquents. Participants were 81 males, 17.46 ± 1.60 years old. Three groups were compared: a juvenile delinquent inmate group (IG), an age-paired group (APG), and an age- and education-paired group (AEPG). A modified Stroop task was used to assess cognitive inhibition and flexibility. The IG and the AEPG (low-education adolescents) had significantly more difficulties than the APG on inhibition; the IG and the AEPG had no significant differences. No group differences were found on flexibility. Since all low-education adolescents have difficulties on inhibition, these difficulties are not an exclusive characteristic of juvenile delinquents. Analysis of cognitive processes in juvenile delinquents must control for education to determine how specific are the difficulties found in these adolescents.     

THE TIMING AND MECHANISMS OF THE OFFENDING‐DEPRESSION LINK*

Why is juvenile delinquency associated with depression in young adulthood? One possibility is that delinquency interferes with socioeco‐nomic attainment and disrupts entry into adult roles, perhaps because of official labeling processes or adolescent socialization into deviance, and these repercussions of delinquency lead to depression. Another possibility is that grown delinquents may show high levels of depression because they tend to offend in adulthood, and adult offenders tend to be depressed. I use data from the National Longitudinal Study of Adolescent Health to examine the timing and mechanisms of the offending‐depression relationship. The results suggest that delinquency is negatively associated with later status attainment and that the status attainment deficits of grown delinquents are not fully explained by justice system contacts or by adolescent delinquent peer influence. A portion of the longitudinal delinquency‐depression link is explained by the low levels of education of grown delinquents and by their involvement with the justice system. Still, young adult depression is more closely tied to recent offending than it is to juvenile delinquency, official labeling, or the status attainment consequences of delinquency.     

NEUROPSYCHOLOGICAL TESTS PREDICTING PERSISTENT MALE DELINQUENCY*

This article reports the first longitudinal evidence that prospective measures of neuropsychological status predict antisocial outcomes. We studied data for a birth cohort of several hundred New Zealand males from age 13 to age 18. Age-13 neuropsychological scores predicted later delinquency measured via multiple sources: police, courts, and self-report. Poor neuropsychological scores were associated with early onset of delinquency. The results fit our predictions about two trajectories of delinquent involvement: (1) Poor neuropsychological status predicted specifically male offending that began before age 13 and persisted at high levels thereafter. (2) By contrast, in this sample neuropsychological status was unrelated to delinquency that began in adolescence.     

IS THE ASSOCIATION BETWEEN ALCOHOL USE AND DELINQUENCY CAUSAL OR SPURIOUS?*

We attempt to isolate the effects of alcohol on different types of delinquent behavior by identifying the spurious portion of the relationship. Using data on adolescents from Finland, we compare the relationship between drinking and delinquent behavior while sober to the total relationship between drinking and delinquent behavior (sober or not). For each type of offense, we find a substantial relationship between drinking and sober delinquency, which suggests a good deal of spuriousness. For crimes of petty theft (shoplifting and stealing from home), the relationship between drinking and sober delinquency is just as strong as the total relationship, which suggests the relationship is almost completely spurious. For violence, vandalism, car theft, and graffiti writing, the alcohol‐sober delinquency relationship is weaker, which suggests that alcohol has a causal effect on these offenses.