Resolution of Nonmarital Adolescent Pregnancy and the Transition to Adulthood: Educational Attainment and Financial Well-being

This paper compares educational and financial outcomes in early adulthood for four groups of men and women: those who never experienced a nonmarital adolescent pregnancy, those who ended a nonmarital adolescent pregnancy by abortion, those who married or cohabited and became parents in response to an adolescent pregnancy, and those who became parents but did not marry or cohabit following an adolescent pregnancy. The analyses are based on self-reports of 6,074 young men and women who were first surveyed as seventh grade students in Houston, Texas in 1971 and surveyed again between 1980 and 1988. Educational and financial outcomes in adulthood vary significantly depending on the occurrence of a nonmarital adolescent pregnancy, the resolution of nonmarital adolescent pregnancy, and the age at which adolescent pregnancy occurs. Results are discussed in relation to public policies encouraging family formation and educational support and occupational training for teen parents.     

The effects of state policy design features on take-up and crowd-out rates for the State Children's Health Insurance Program.

We evaluate the effects of state policy design features on SCHIP take-up rates and on the degree to which SCHIP benefits crowd out private benefits. The results indicate overall program take-up rates of approximately 10 percent. However, there is considerable heterogeneity across states, suggesting a potential role of inter-state variation in policy design. We find that several design mechanisms have significant and substantial positive effects on take-up. For example, eliminating asset tests, offering continuous coverage, simplifying the application and renewal processes, and extending benefits to parents all have sizable and positive effects on take-up rates. Mandatory waiting periods, on the other hand, consistently reduce take-up rates. In all, inter-state differences in outreach and anti-crowd-out efforts explain roughly one-quarter of the cross-state variation in take-up rates. Concerning the crowding out of private health insurance benefits, we find that between one-quarter and one-third of the increase in public health insurance coverage for SCHIP-eligible children is offset by a decline in private health coverage. We find little evidence that the policy-induced variation in take-up is associated with a significant degree of crowd out, and no evidence that the negative effect on private coverage caused by state policy choices is any greater than the overall crowding-out effect. This suggests that states are not augmenting take-up rates by enrolling children that are relatively more likely to have private health insurance benefits.     

Problem boys in young adulthood: Teachers' ratings and twelve-year follow-up

In an earlier paper we reported that teachers' ratings of child guidance clinic children were associated with the children's global adjustment in young adulthood. Teachers' ratings, especially the peer relations measure, far surpassed other data sources in predicting general adult mental status. Other sources were developmental history, social history, family information, and psychiatric and psychological evaluations. The purposes of the present investigation were to evaluate mother-son reliability on adulthood information, and to determine whether teacher-rated behaviors of clinic boys predicted specific adult behaviors or were only globally related. Interviewed separately when sons were young adults, mothers and sons closely agreed on sons' adult behavior, with mothers somewhat underreporting sons' negative behaviors. The major finding was that one teacher-rated item,fails to get along with other children, was closely associated with a wide spectrum of adult behaviors. This was not due to the peer relations indicator serving as a global statistic reflecting general childhood impairment. It was also found that composite scores of childhood and adulthood bad conduct were significantly related to each other.Data collection was funded by NIMH Grant #MH-23441-02A1, and by the William T. Grant Foundation, Loretta K. Cass, Principal Investigator. The authors bear sole responsibility for the data analyses and interpretation presented here.Received Ph.D. from University of Oklahoma. Current research interests are in prediction of adult mental status from childhood indexes.Received Ph.D. from Washington University. Current research interests are in life history research, particularly alcoholism and schizophrenia.Received B. A. from Washington University.     

Detection of a primer-binding site polymorphism for the STR locus D16S539 using the Powerplex 1.1 system and validation of a degenerate primer to correct for the polymorphism

Quality assurance samples submitted from the NCSBI as part of a contract with TBTG to outsource DNA Database samples showed unexpected discrepancies for the locus D16S539 when all other loci yielded identical results. Discrepancies observed included allele drop out and an imbalance in sister alleles with samples returned from TBTG. This led to a comprehensive review of the technical procedures used between the two laboratories to determine the cause of the discrepancies noted for the locus D16S539, since both laboratories were using the PowerPlex 1.1 typing kit from the Promega Corporation. The NCSBI and the TBTG utilize different extraction methods (organic extraction vs. FTA) and amplification conditions (AmpliTaq vs AmpliTaq Gold), respectively, so the exact cause of discrepancy observed was not immediately apparent. Experiments at the NCSBI associated the observed allele drop out and the imbalance of the sister alleles with the use of AmpliTaq Gold and a hot start procedure. Sequencing data revealed that a point mutation resides on the D16S539 primer-binding site that reaches polymorphic levels in African-American populations. This led to the development of a degenerate primer by the Promega Corporation to detect "missing" alleles when AmpliTaq Gold is used. The degenerate primer was then thoroughly tested to show its efficacy in detecting the "true" D16S539 profile when used.     

Skin penetration assessment of less lethal kinetic energy munitions

The development of less-lethal technologies has provided law enforcement personnel with an alternative to lethal force. Although the less lethal projectile was produced to engender non-penetrating wounds, case studies show that there have been a number of reported penetrating injuries ranging from minor to significant in morbidity. The objective of this study was to determine the energy per unit area required to penetrate various regions of the body. Eight unembalmed postmortem human specimens were procured for this testing. Each specimen sustained a maximum of 25 impacts consisting of shots to the anterior and posterior thorax, abdomen, and legs. A 12-gauge, fin-stabilized, rubber rocket round was used as the impactor for all of the conducted tests. The energy density required for 50% risk of penetration varied from 23.99 J/cm2 for the location on the anterior rib (p = 0.000) to 52.74 J/cm2 for the location on the posterior rib (p = 0.001).     

An updated validation of Promega's PowerPlex 16 System: high throughput databasing under reduced PCR volume conditions on Applied Biosystem's 96 capillary 3730xl DNA Analyzer

The PowerPlex 16 System from Promega Corporation allows single tube multiplex amplification of sixteen short tandem repeat (STR) loci including all 13 core combined DNA index system STRs. This report presents an updated validation of the PowerPlex 16 System on Applied Biosystem's 96 capillary 3730xl DNA Analyzer. The validation protocol developed in our laboratory allows for the analysis of 1536 loci (96 x 16) in c. 50 min. We have further optimized the assay by decreasing the reaction volume to one-quarter that recommended by the manufacturer thereby substantially reducing the total cost per sample without compromising reproducibility or specificity. This reduction in reaction volume has the ancillary benefit of dramatically increasing the sensitivity of the assay allowing for accurate analysis of lower quantities of DNA. Due to its substantially increased throughput capability, this extended validation of the PowerPlex 16 System should be useful in reducing the backlog of unanalyzed DNA samples currently facing public DNA forensic laboratories.     

Sudden Cardiac Death in a Young Man with Migraine-associated Arrhythmia

A 31-year-old man with migraine-induced syncope and bradycardia with subsequent pacemaker implantation died unexpectedly. Clinically unsuspected cardiac anomalies were found at autopsy including myocardial bridging of the left anterior descending artery and shelf-like coronary artery ostia. Nortriptyline was identified by toxicologic analysis. A review of the autopsy findings, the historical information, and the effects of the possible arrhythmogenic circumstances is undertaken and the potential contributions to the death are discussed. Cardiac arrhythmias have been documented during migraines. Coronary artery bridging has been known to lead to ischemia and infarction, ventricular tachycardia, and sudden death; however, these are very rare sequelae. Congenital coronary artery anomalies have been linked to sudden cardiac death, but only rarely cause death in people younger than 31 years. Migraines and the autopsy findings described have been associated with cardiac arrhythmia and sudden death. Altogether, they led to the unexpected death of this young man.