SMART:自主研发的混合STR图谱分析系统

目的混合STR图谱的分析是法医遗传学领域的一个难题。目前国内大多数法医DNA实验室依靠人工方法分析混合STR图谱,费时费力,且拆分效果也多有主观性,难以满足日益增长的混合STR图谱分析的需求。本文介绍一套自主研发的混合STR图谱分析系统——SMART(STR Mixture Analysis and Resolution Tools),其能够实现对混合STR图谱的自动化分析,包括拆分混合STR图谱和计算似然比。方法SMART使用的STR峰高的概率模型,考虑了影子峰、降解、基因座特异性扩增效率、峰高变异、插入峰、峰丢失等因素。模型通过比较各个基因型集合拟合当前混合STR图谱的似然值大小来推断最有可能的基因型集合,采用了马尔可夫链蒙特卡洛(MCMC)算法进行求解。结果SMART可应用于不同试剂盒和遗传分析仪产生的数据。经使用ABI-3500XL遗传分析仪和Global Filer试剂盒测试,SMART能够实现对2~5人的混合STR图谱的分析,输出包括混合比例、混合图谱质量、各个贡献者单人的STR基因分型、似然比等多项结果。结论SMART作为一款自主研发的混合STR图谱分析系统,其基本涵盖了国外同类分析系统所具有的功能,技术性能指标达到国际先进水平,能够满足一线法医工作者对于混合STR图谱分析的多样化需求,提高混合STR图谱结果的利用率。     

Reproductive health services: “Business-in-a-Box” as a model social innovation

Access to reproductive health services and products in remote and rural communities is a critical area of concern for developing countries. This article considers a pilot intervention in three districts of Pakistan where “Business-in-a-Box” as a model of place-based social innovation is used to improve the socio-economic conditions of women in remote rural settings through socially responsible micro-franchising. It finds that such programmes help build a sense of community, ownership and grassroots capabilities and skills. The article also discusses the impacts of such actions on the individual and community life, and the need to upscale and sustain these initiatives.     

浮动抵押逸出担保物权体系的理论证成

具有担保功能的权利,并非都是担保物权。如果一项权利既不符合担保物权的特征,亦有违物权法的基本原则,就不属于担保物权。对比浮动抵押与担保物权的特征可以发现,浮动抵押有担保功能但并非担保物权。在民法典编纂背景下,宜将浮动抵押从担保物权体系剔除。考察比较法资料,结合“charge”的词源语义,遵循语言翻译的忠实严谨原则,宜将“floating charge”译为“浮动担保”而非“浮动抵押”。至于浮动担保何去何从,相对合理的方案是将其嵌入合同法域,规定于我国民法典合同编之“合同的担保”章节,以此彰显民法典的体系性与逻辑性。     

新冠肺炎疫情期间公安法医应当加强尸体甄别和个体防护

因鉴定体制特点,公安法医除参与尸体有关的现场勘查工作外,还需进行尸体检验工作。在此过程中,可能面对很多风险,受伤和中毒等事件时有发生。然而,国内公安法医对新冠肺炎等传染病流行期间死亡的尸体如何甄别进行尸体检验鉴定,对现场勘查及尸体检验工作的防护只有少量规定,且内容不够详尽。本文对法医在现场勘查中遇到的尸体及尸体检验中实验室建设、职业现状、风险评估及防范措施等进行了论述。最后,建议出台相关的制度规定等具体约束规范措施,以保障公安法医现场勘查及尸体检验工作的顺利进行,以解除基层鉴定机构和鉴定人的后顾之忧。     

美国国家安全情报传递机制论析

作为世界上情报体系最为发达的国家，美国国家安全情报机制一直以来备受各方关注。九一一事件催生了美国情报体系全面而彻底的改革。经过十多年的努力，美国情报界实现了从机构林立的分散体系到由国家情报总监办公室领导的有机整体的重大转型。从总体机制来看，美国情报界现已形成情报机构一体化与任务一体化的双轮驱动体系，其情报传递网络不仅涵盖领导、协调、执行三个层级间的纵向传送，而且包括不同情报机构之间的横向协调，基本实现了情报整合与信息共享。美国国家情报总监办公室成为名副其实的美国情报界统领，其下设的反恐、反扩散、反情报和网络情报中心构成了美国国家安全情报分类传递机制的四大支柱。通过比较，四大分类传递机制中最为成熟的是反恐中心，其次是反情报与安全中心，再次是网络威胁情报整合中心，最后是反扩散中心。由于各类情报机制自身发展程度的不同，其改革过程中所面临的挑战也不一样。美国国家安全情报传递机制的改革“瓶颈”既有发展不足导致的结构性困境，也有外部安全环境变化带来的挑战。此外，特朗普政府上台后的一系列政策举措使得美国国家安全情报体系的发展方向呈现出新的态势。     

防范化解政治领域重大风险探析

政治安全是国家安全的根本。维护国家政治安全,是新时代进行伟大斗争的必然要求,是实现中华民族伟大复兴中国梦的重要保障。当前,我国政治安全形势总体保持稳定、向好的基本态势,但同时面临的风险与挑战也是前所未有的,影响政治安全的不利因素日趋复杂。必须坚持底线思维,增强忧患意识,认真贯彻落实总体国家安全观,加强有针对性的防范打击,坚决消除一切影响国家政治安全的隐患,确保党的执政安全和中国特色社会主义制度安全。     

British Campaigns for Solidarity with Argentina and Chile

The Chile solidarity movement persuaded British Labour governments (1974–1979) to introduce a range of measures against the Pinochet regime. But campaigners lobbying against the Argentine dictatorship (1976–1983) had less impact on policy. Neither these Labour governments nor the subsequent Conservative government imposed any sanction on the Argentine dictatorship, until the invasion of the Falkland Islands. This article explores why in Britain – and Europe – the Chile campaign had greater public appeal than the Argentina solidarity campaigns. It identifies a number of common factors across Europe which explain why the anti-Pinochet cause generated more support than the Argentina campaign.     

Terrorist violence and the enrollment of psychology in predicting Muslim extremism: critical terrorism studies meets critical algorithm studies

Discourse on terrorist violence has long facilitated an especially liberal form of securitisation. Originally evoked in reference to anarchists and communists, a rational consideration of terrorist violence, inaugurated by the concept, asks for deferred judgement about the nature of, or reasons behind, violence related to terror on the premise that state and international legal norms governing the legitimate use of violence fail to circumscribe the proper capacities of the state to regulate and explain terrorism. Where sovereign powers along with their military and civilian instruments of coercion are deemed unable to regulate violence effectively, analysts of terrorist violence and their readership are invited to consider and cultivate new sensibilities. Beginning in the 1980s, studies by psychologists found renewed urgency among a growing cadre of interdisciplinary terror experts who found religion, Islam especially, a key variable of analysis. I situate their contributions in a longer history of secular and racialising discourse about terrorist violence. Central to this history are practices of reading, translating, interpreting and archiving texts. Evidence for the argument is based on the analysis of an algorithm that allegedly predicts the likelihood of terrorist strikes by counting words spoken by al-Qa?ida leaders and correlating their frequency with over 30 psychological categories.     

Rising to the Challenge: Europe’s Security Policy in East Asia amid US-China Rivalry

ABSTRACT

China’s growing power and assertiveness towards its smaller and weaker neighbours has been a wakeup call for the European Union and its member states which, as a result, have stepped up their involvement in East Asia. EU security policy in the region shows many elements of alignment with the United States, but also differences. In North East Asia, the EU has adopted harsh sanctions against North Korea but, contrary to the Trump administration which continues to seek regime change, has left the door open for dialogue. Moreover, the EU supports the process of trilateral cooperation among China, Japan and South Korea, while Washington has traditionally been lukewarm towards a process that excludes the US and risks being dominated by Beijing. The transatlantic allies also show differing approaches with regard to maritime disputes in the South China Sea. While EU security policy in East Asia is largely complementary to that of Washington, in some cases Europe tends – albeit inadvertently – to favour Beijing.     

非洲和平与安全建设：南非的区域大国角色及限度*

作为区域大国,南非在非洲安全秩序构建中发挥着重要作用。1994年民主转型后,南非国家身份定位由西方的"白人飞地"转变为"非洲国家","以非洲为中心"成为南非外交政策的战略优先。南非非国大政府秉持新的国家身份认知,不再将非洲国家视为国家安全的威胁,而是命运与共的合作伙伴。南非通过参与解决非洲国家冲突、加强非洲集体安全机制建设、支持非洲冲突后重建与发展进程、推动联合国与非盟加强战略协调与合作、参与多边维和行动等方式参与非洲和平与安全建设,扮演了区域安全公共产品供给者的角色。南非虽然在非洲和平与安全建设的某些领域发挥了独特的引领作用,但经济增长乏力和国力相对下降,使其越来越无法有效应对日趋复杂的非洲安全形势。域外大国和国家集团加大对非洲安全事务的干预力度、其他非洲区域大国的竞争,也对南非在非洲和平与安全建设领域发挥引领作用形成了制约。在新冠肺炎疫情冲击、经济增长陷入衰退和社会矛盾加剧的背景下,南非政府将把更多精力和资源用于解决国内经济和社会发展问题,直接介入非洲冲突解决的意愿和能力会有所下降。南非在参与非洲安全事务过程中将更加惜用自身国内经济军事资源,进一步提升对外交手段、非洲集体安全机制的依靠。